Desmethylcitalopram-d3 (hydrochloride)

Desmethylcitalopram-d3 (hydrochloride) - Names and Identifiers

Name	rac Demethyl Citalopram-d3 Hydrochloride
Synonyms	Desmethylcitalopram-d3 (hydrochloride) rac Demethyl Citalopram-d3 Hydrochloride [2H3]-- (±)-Demethyl Citalopram Hydrochloride 1-[3-(Methylamino-d3)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile 1-(4-Fluoro-phenyl)-1-[3-(methyl-d3)amino-propyl]-1,3-dihydro-isobenzofuran-5-carbonitrile Hydrochloride
CAS	1189650-18-7

Desmethylcitalopram-d3 (hydrochloride) - Physico-chemical Properties

Molecular Formula	C19H20ClFN2O
Molar Mass	346.8263032
Melting Point	78-80°C
Solubility	Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
Appearance	Solid
Color	White to Pale Beige
Storage Condition	Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Stability	Hygroscopic

Desmethylcitalopram-d3 (hydrochloride) - Introduction

rac Demethyl Citalopram-d3 Hydrochloride (levodesmethylcitalopram-d3 Hydrochloride) is a drug substance. The following is a description of its nature, use, preparation and safety information:

Nature:
rac Demethyl Citalopram-d3 Hydrochloride is a compound in the form of a chloride salt with three deuterium (d3) in its chemical structure. It is a white or almost white crystalline powder, soluble in water and some organic solvents.

Use:
rac Demethyl Citalopram-d3 Hydrochloride is a labeled compound commonly used in the field of biomedical research, especially in pharmacokinetic studies. It can be used as an internal standard substance for the metabolites of citalopram for quantitative analysis.

Preparation Method:
rac Demethyl Citalopram-d3 Hydrochloride is generally prepared by chemical synthesis. First, an appropriate starting material is reacted with hydrofluoric acid to form a trideuterated hydrofluoride salt. The corresponding hydrochloride salt is then formed by reaction with a solution containing citalopram chloride. Finally, the target product is obtained by purification and drying.

Safety Information:
rac Demethyl Citalopram-d3 Hydrochloride has less safety information because it is mainly used in laboratory research and not in human clinical applications. However, in general, the use of this substance should be followed by laboratory safety procedures. Attention should also be paid to appropriate personal protective measures, including the wearing of gloves, glasses and outside laboratory work clothes. If you accidentally splash into your eyes or skin, rinse immediately with plenty of water and seek medical attention.

Please note that this information is for reference only. The specific operation and use should follow the relevant regulations and safety guidelines, and be carried out under the guidance of professionals.

Last Update：2024-04-09 21:01:54